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artemether/lumefantrine will reduce the extent or impact of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.cenobamate will improve the amount or result of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Monitor Closely. Take into account a dose reduction of CYP2C19 substrates, as clini